CBD can interact with certain medications. Here's what you need to know about CBD and drug interactions.
How CBD Affects Medications
CBD inhibits cytochrome P450 enzymes (especially CYP3A4 and CYP2D6) in the liver. These enzymes metabolize many medications. When inhibited:
- Some drugs may stay in your system longer
- Drug levels may increase
- Side effects may become more pronounced
Medications That May Interact
Higher Concern:
- Blood thinners (warfarin, heparin)
- Heart medications (antiarrhythmics)
- Benzodiazepines (Xanax, Valium, Klonopin)
- Immunosuppressants
- Some HIV antivirals
Moderate Concern:
- Some antidepressants
- Some antipsychotics
- Certain statins
- Some seizure medications
The Grapefruit Rule
Simple guideline: If your medication has a "grapefruit warning," it may also interact with CBD (same enzyme pathway).
Safety Guidelines
- Always consult your doctor before adding CBD to medications
- Start with low CBD doses
- Monitor for increased side effects
- Your doctor may need to adjust medication doses
- Get regular blood work if on monitored medications
When to Avoid CBD
- Without doctor approval if on blood thinners
- Before surgery (may affect anesthesia)
- If experiencing unusual symptoms after starting CBD
Why Herbiez Hemp Co
- ✓ Third-party lab tested
- ✓ Farm Bill compliant
- ✓ Fast Nebraska shipping
- ✓ Responsive support
Disclaimer: For informational purposes only. Not medical advice.